Pregnenolone cream connected topically is indicated to bolster solid body capacities and hormone levels. Pregnenolone is the concoction forerunner of different hormones; including the estrogens, testosterone, progesterone, cortisol, DHEA (dehydroepiandrosterone) and aldosterone.

A few people use pregnenolone cream items for agony and weariness. Men utilize this prohormone essentially to support their creation of testosterone. Ladies use it to ease perimenopausal manifestations; like hot flashes, rest issues and vaginal dryness.

Human examination on pregnenolone cream and supplements is extremely restricted. To date, there is no dependable data concerning the impacts of pregnenolone regulated exogenously (outside the body).

There are various famous pregnenolone cream items sold on Amazon. The smash hit item is Life-Flo Pregnenolone, which has a 4.3 out of 5-star rating, in view of 42 client audits.

What is Pregnenolone?

Pregnenolone is a characteristic substance created from cholesterol. It assumes an essential part in adrenal capacity, sexual capacity and supporting the body’s capacity to react to push.

Pregnenolone levels in people tend to decrease strongly with age. In numerous individuals, levels start to drop off after the age of 35 years. By age 55, the body is delivering around 30% short of what it did at 35. Furthermore, by the age of 70, pregnenolone creation rates diminish by around 60%.

Pregnenolone supplements and creams have been showcased for boosting levels of this steroidal hormone. These supplements are some of the time advanced for adrenal exhaustion, maturing, sexual execution and weight reduction.

There is no institutionalized definition of pregnenolone creams. Different qualities are advertised, from 10 to 150 mg.

Pregnenolone Cream Research

A hunt of PubMed yields just 2 results for the pursuit term “pregnenolone cream”. No edited compositions or information is accessible from the studies. One was led in Germany and the other in Czechoslovakia.

There have been more than 6000 studies on the impacts of Pregnenolone in the body. Notwithstanding, the vast majority of these studies have taken a gander at the impacts of endogenous Pregnenolone that is fabricated in the body.

There has not been as much research into the utilization of oral Pregnenolone supplements for boosting levels of this hormone. Its belongings keep on being investigated concerning nervousness, dejection, schizophrenia, cannabis inebriation, liquor addiction, steroid union and that’s just the beginning.

Research demonstrates that individuals with emotional issue are prone to have low levels of pregnenolone in their cerebrospinal liquids. This appears to be particularly valid in those encountering dynamic depressive scenes.

One study demonstrated that pregnenolone can influence the length of moderate wave rest stages. This impact is accepted to be brought on by impelling adversarial exercises of GABA (gamma-aminobutyric corrosive) receptors inside the mind.

Pregnenolone Cream Employments

Pregnenolone creams are regularly taken for against maturing impacts. This item is publicized to, “Advance solid young parity.”

A few people use pregnenolone to help vitality and expansion general prosperity. Others consider pregnenolone supportive for upgrading memory and thought clarity, however more research is expected to accept this case.

In rodents, pregnenolone exhibits solid memory-enhancing impacts. It is conceivable that it builds a mind concoction called acetylcholine in the hippocampus.

Be that as it may, this outcome should be reproduced in people before any conclusive memory-upgrade cases can be made.

Pregnenolone Cream for Menopause

In ladies who are going to enter menopause, levels of estrogen start to decay. In a few ladies, this causes vaginal dryness, hot flashes, dry skin and certain different side effects.

Some perimenopausal ladies use pregnenolone cream items since they may help DHEA levels, which thusly may raise estrogen levels.

Be that as it may, pregnenolone cream may likewise raise testosterone levels and cause manifestations like skin break out, undesirable hair development (hirsutism) and fractiousness.

Pregnenolone Cream for Men

Men regularly utilize pregnenolone cream items to actually raise testosterone levels. Testosterone is the essential male sex hormone in charge of regulating bulk and muscle to fat ratio ratios. It is additionally basic for keeping up sound moxie (sex drive), sperm tally and penis erectility.

Some pregnenolone gets changed over to progesterone, and hence to testosterone. Other progesterone gets changed over to estrogen. Men with bosom expansion (gynecomastia) regularly have low testosterone and over the top estrogen. Pregnenolone cream may adjust these sex hormones.

Research recommends that levels of progesterone and testosterone appear to increment and decay together. Case in point, when men are sexually excited, levels of both chemicals increment. Pregnenolone cream use may build progesterone union in the body.

Progesterone is known not 5-alpha-reductase; the compound used to change over testosterone into DHT (dihydrotestosterone). Exorbitant DHT is one of the reasons for male issues like amiable prostatic hyperplasia, prostate disease and male example hair sparseness. Restraining 5-alpha-reductase advances upregulated testosterone union.

Pregnenolone Cream Reactions

Utilizing pregnenolone cream items accompanies certain dangers for antagonistic symptoms. In men, the most widely recognized reactions incorporate forceful conduct, male pattern baldness and hoisted estrogen levels.

Other basic pregnenolone cream symptoms for men and ladies incorporate application site skin disturbance, fast pulse and overstimulation. Different potential outcomes incorporate obscured vision, dazedness, uneasiness and annoyance.

Reactions might will probably happen when utilizing this item for drawn out stretches of time. A few specialists prescribe utilizing this supplement for close to two weeks on end and consistently taking breaks from its utilization.

Pregnant and nursing ladies ought not utilize pregnenolone creams. Individuals with certain therapeutic conditions ought to likewise stay away from use. Some of these incorporate coronary illness, broadened prostate and hormone-delicate tumor.


Pregnenolone cream items are common supplements which are not explored by the US FDA. No institutionalized dosing suggestions have been set up.

Hormones like pregnenolone can have capable impacts. Slight modifications in their levels can yield major physiological impacts. Dosages as low as 1 mg may bring about critical impacts. Continuously cycle off utilization occasionally to lessen odds of unfavorable impacts.

There is right now no clinical confirmation that pregnenolone creams can enhance wellbeing in any capacity. On the off chance that you trust that utilizing pregnenolone cream may advantage you, then converse with your specialist about it. Make certain to specify all prescriptions, herbs and/or supplements you may utilize.